Summary
Overview
Work History
Education
Skills
Patents
Data Worked With
Concepts
Publications
Accomplishments
Certification
Timeline
Intern

Ishita Mallick

Associate Scientific Manager
Pune

Summary

Ishita Mallick is a biotechnologist by training and life science domain consultant by profession. Ishita is actively involved in developing AI based solutions for addressing the pain areas of Global Pharma/biotech clients. Ishita works on bridging the gap between Pharma & IT, understanding complex business requirements of the industry and proposing solutions specific to business needs. Prolific, high-energy Product Manager delivers comprehensive project management support and oversight across multiple functional areas. Uses technical expertise to support research reports, presentations and data analysis. Exhibits strong cross-functional collaboration while understanding scientific rationale driving projects.

Overview

6
6
years of professional experience
5
5
years of post-secondary education
1
1
Certification
4
4
Languages

Work History

Associate Scientific Manager (Drug Discovery)

Innoplexus Consulting Services
Pune
01.2023 - Current
  • Product manager for 2 products (target identification and antibody-drug conjugate)
  • Periodic assessments and initiatives to enhance and optimize existing features in pipeline
  • Orchestrated collaboration between diverse teams including data scientists and data engineers to ensure seamless execution of ideas
  • Demonstrated proficiency in project management tools such as JIRA software to meticulously track tasks, allocate resources, and manage timelines
  • Successfully optimized workflows to enhance efficiency and productivity in feature development
  • Effectively communicates impact and value proposition of developed features, fostering buy-in and support for product initiatives

Key achievement in product development:

  • Managed and developed target identification pipeline along with technical experts and automated manual efforts to reduce run time of pipeline from several month's time to few weeks
  • Developed world's 2nd largest database of antibody-drug conjugates (UI under development)
  • Supervised and trained team of 30 people by conducting weekly sessions related to personality development, basic excel skills, PowerPoint presentations, client management
  • Guided ideation of linker prediction model for antibody-drug conjugate product

Client deliveries and pipeline developments

  • Successfully led 6 client projects related to disease expansion and prioritization and target identification
  • Initiated and prepared base pipeline for development of pharma company pipeline drug review to identify and recommend failed drug assets
  • Risk-mitigation and proposal plans related to ontology issues

Sr. Research Analyst (Bioinformatics)

Innoplexus Consulting Services
Pune
01.2021 - 12.2022

Project development & delivery:

  • Sub-lead of target identification module
  • Developed and presented more than 20 domain case studies on AI generated hypotheses to clients
  • Automation planning and execution for target identification module: Supervised team of 5 people to build pipeline for delivering target identification projects
  • Guided and automated more than 5 disease and target relevant parameters which was integrated as part of weightage-based scoring system in target identification pipeline
  • Insight generation & validation: Assessment of a highly modular disease-target association library using biomedical literature and external analysis tools
  • Project effort estimation and SOP preparation: Fairly experienced in task generation and allocation on JIRA
  • Experienced in preparing gantt chart for planning milestone deliveries
  • Experienced in preparing SOPs of several drug discovery modules.

Knowledge Associate (Bioinformatics)

Innoplexus Consulting Services
Pune
04.2019 - 12.2020
  • Trained and led team of 10 junior knowledge associates to provide support in client deliverables
  • Contributed to quality enhancement of backend knowledge required for commercial products and projects delivered to pharmaceutical clients
  • Worked on more than 2000 physician & hospitals data to remove name normalization issues and prepare standard training datasets for machine learning models
  • Enriched information and solved issues pertaining to biomedical literatures comprising of publications, clinical trials, news, patents, thesis & grants.

Junior Knowledge Associate

Innoplexus Consulting Services
Pune
10.2018 - 03.2019
  • Literature review of asset classes like publication, clinical trials, patents, news, grants
  • Worked in data curation and validation team to curate information related to authors and affiliations and correctness of data ported on proprietary platform
  • Sentiment analysis of life science data on proprietary platform
  • Worked on data cleaning and normalization related to drug names
  • Key opinion leader (KoL) data curation and validation from congresses
  • Internal product validation to check data correctness and accuracy

Education

Master of Science - Biotechnology

Modern College
Pune
07.2016 - 05.2018

Bachelor of Science - Biotechnology

Nowrosjee Wadia College
Pune
07.2013 - 05.2016

Skills

Product management

Patents

  • Method and system for evaluating potential drug compositions for target disease (US20220020465A1)
  • Determining drug combinations, synergistic drug combination and use thereof in pancreaticcancer treatment (US20220016116A1)
  • Phosphoinositide 3-kinase and src inhibitors for treatment of pancreatic cancer (US20220016123A1)

Data Worked With

  • Molecular biology: DrugBank, drugs.com, Chembl, Pharos, OpenTarget, Drug gene interaction database, Therapeutic target database, Genecards, Malacards, STRING, MINT, Biogrid, IntAct
  • Genomics data: GEO, ArrayExpress, ClinVar, GWAS central, NCBI
  • Clinical trials: Clinical trial.gov, EUCTR
  • Pathways: KEGG, Reactome, Wikipathways, HumanCyc
  • Biomedical literature: PubMed, PMC, Wiley, NCBI
  • Patents and regulatory bodies: FDA, USPTO
  • Protein structure: PDB
  • Adverse events: FEARS, VigiAccess
  • NCBI

Concepts

  • Literature mining
  • Expression analysis
  • Enrichment analysis
  • Name normalization
  • Network analysis
  • Gene ontology enrichment
  • Clinical trial analysis
  • Drug repurposing
  • Ontology
  • Adverse events
  • Target identification
  • Indication prioritization
  • Standard operating procedure(SOP)

Publications

First author: "In-silico identification and prioritization of therapeutic targets of asthma" in Nature Scientific Reports 21 September 2023

Accomplishments

    1. Represented Innoplexus in the 18th India-Japan collaboration conference (BICON 2023): Nurturing Academic Entrepreneurs with Industrial Partnerships


    2. Presented at the Indian Pharmaceutical Association Student's Forum delving into the world of life science data analysis for impactful insights

Certification

Digital Product Management: Modern Fundamentals course offered by UVA Darden School of Business

Timeline

Digital Product Management: Modern Fundamentals course offered by UVA Darden School of Business

11-2023

Associate Scientific Manager (Drug Discovery)

Innoplexus Consulting Services
01.2023 - Current

Sr. Research Analyst (Bioinformatics)

Innoplexus Consulting Services
01.2021 - 12.2022

Knowledge Associate (Bioinformatics)

Innoplexus Consulting Services
04.2019 - 12.2020

Junior Knowledge Associate

Innoplexus Consulting Services
10.2018 - 03.2019

Master of Science - Biotechnology

Modern College
07.2016 - 05.2018

Bachelor of Science - Biotechnology

Nowrosjee Wadia College
07.2013 - 05.2016
Ishita MallickAssociate Scientific Manager